ກໍລະນີຂອງການຕິດເຊື້ອຮ່ວມກັບສອງ variants ໄດ້ຖືກລາຍງານກ່ອນຫນ້ານີ້. ບໍ່ເປັນທີ່ຮູ້ຈັກຫຼາຍກ່ຽວກັບການລວມຕົວຂອງເຊື້ອໄວຣັສທີ່ໃຫ້ຜົນຜະລິດໄວຣັສທີ່ມີ genomes ປະສົມ. ສອງການສຶກສາທີ່ຜ່ານມາລາຍງານກໍລະນີຂອງການປະສົມພັນທຸກໍາລະຫວ່າງ SARS-CoV-2 variants Denta & Omicron. recombinant, ເອີ້ນວ່າ Deltamicron, ມີລັກສະນະຂອງທັງສອງ variants.
ໄລຍະ 'Deltacron' ປາກົດຢູ່ໃນຕົ້ນປີນີ້1 to denote COVID-19 cases of co-infection of people with the different variants of SARS-Cov-2 variants, e.g. delta and omicron. Delmicron or Deltacron referred to the infection caused by a combination of “two variants of the same strain of virus, SARS CoV-2″, and were not said to be different “strains".
However, cases of genetic recombination between two different strains of SARS, ດິຈິຕອ, 2 have been reported recently. On 08 March 2022, researchers2 reported three infections in southern France with “Deltamicron” recombinant with hybrid genome that had spike protein from an Omicron variant and the “body” of a Delta variant. The hybrid genome had signature mutations of the two lineages. The recombinant spike could optimise viral binding to the host cell membrane.
Evidences for Delta and ໂອເມີນີນ recombination has emerged from USA3 as well. This team could identify two independent cases of Delta-Omicron recombinant. In both cases, the 5′-end of the viral genome was from the Delta genome, and the 3′-end from Omicron.
It is suggested that the recombinant viruses are not common nor there is any evidence to suggest that the recombinants with hybrid genomes are more transmissible or virulent than the dominant circulating variants.
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ເອກະສານ:
- Deltacron ບໍ່ແມ່ນສາຍພັນໃໝ່ ຫຼືຕົວແປ. ວິທະຍາສາດເອີຣົບ. ປະກາດໃນວັນທີ 9 ມັງກອນ 2022. ມີຢູ່ http://scientificeuropean.co.uk/covid-19/deltacron-is-not-a-new-strain-or-variant/
- Colson, P., et al 2022. ວັດທະນະທໍາ ແລະການກໍານົດ “Deltamicron” SARS-CoV-2 ໃນກຸ່ມສາມກໍລະນີໃນພາກໃຕ້ຂອງຝຣັ່ງ. ພິມ medRxiv. ປະກາດໃນວັນທີ 08 ມີນາ 2022. DOI: https://doi.org/10.1101/2022.03.03.22271812
- Bolze A., et al 2022. ຫຼັກຖານສໍາລັບການຕິດເຊື້ອ SARS-CoV-2 Delta ແລະ Omicron ຮ່ວມກັນແລະການປະສົມໃຫມ່. ພິມ medRxiv. ປະກາດໃນວັນທີ 12 ມີນາ 2022. DOI: https://doi.org/10.1101/2022.03.09.22272113
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