ການໂຄສະນາ

Fern Genome Decoded: ຄວາມຫວັງສໍາລັບຄວາມຍືນຍົງດ້ານສິ່ງແວດລ້ອມ

Unlocking the genetic information of a fern could provide us potential solutions to multiple issues faced by our ດາວ ໃນມື້ນີ້.

In genome ລໍາດັບ, DNA sequencing is done to determine the order of nucleotides in every specific DNA molecule. This exact order is of value to be able to understand the type of genetic information carried in the DNA. Since genes encode for protein which are responsible for most body functions, this information can help to understand the effect of their function in the body. Sequencing complete genome of an organism i.e. all of its DNA is a complex and challenging task and has to be done bit by bit by breaking DNA into smaller pieces, sequencing them and then putting it all together. For example, the complete human genome was sequenced in 2003 took 13 years and a total cost of USD 3 billion. With advancement in technology genomes can be sequenced relatively faster and at a lower cost using methods like Sanger sequencing and Next-generation sequencing. Once a genome is sequenced and decoded, unlimited possibilities open up for identifying potential areas of biological research and making progress towards targeted application development.

A team of 40 researchers from Cornell University and around the world have sequenced the full genome ຂອງນ້ໍາ ຜັກກູດ ເອີ້ນວ່າ Azolla filiculoides1,2. This fern is commonly seen to be growing in warmer temperatures and tropical regions of the world. The project of unravelling genomic secrets of the fern has been in the pipeline for a while and was backed by funds of USD 22,160 from 123 backers through a crowdfunding site called Experiment.com. Researchers eventually received funding to carry out the sequencing from Beijing Genomics Institute in collaboration with Utrecht University. This tiny floating fern species which fits over a finger nail has a genome size of .75 gigabases (or billion base pairs). Ferns are known to have large genomes, average of 12 gigabases in size, however none of the larger fern genomes have been decoded so far. Such an elaborate project was aimed at providing clues on what could be the potential of this fern.

Many interesting aspects of fern Azolla have been uncovered upon this genome sequencing study published in ພືດ ທຳ ມະຊາດ and have provided direction for future research on potential areas in which this fern can be beneficial. The fern Azolla was widespread and growing almost 50 million years ago on this ດາວ around the Arctic Ocean. During that time Earth was also warmer compared to current conditions and this fern was thought to play a significant role in keeping the ດາວ cooler by capturing around 10 trillion tons of carbon dioxide from the atmosphere over the course of 1 million years. Here we see a potential role for this fern in combating and protecting our ດາວ from global warming resulted by climate change.

The fern is also thought to play an important role in nitrogen fixation, a process which combines free nitrogen (N2) in the atmosphere – an inert gas available abundantly in air – with other chemical elements to create more reactive nitrogen-based compounds e.g. ammonia, nitrates etc which can then be used in various applications like fertilizer for agriculture purposes. ກຳ ມະພັນ data tells us about a symbiotic relationship (mutual benefit) of this fern with a cyanobacteria named Nostoc azollae. The fern leaf host these cyanobacteria in tiny holes and these bacteria fix nitrogen thereby producing ອົກຊີເຈນ ທີ່ຜັກກູດແລະພືດທີ່ເຕີບໃຫຍ່ຢູ່ອ້ອມຂ້າງສາມາດນໍາໃຊ້ໄດ້. ໃນທາງກັບກັນ, cyano ເຊື້ອແບັກທີເຣັຍ gather energy through the plant photosynthesis when the fern provides it fuel. Therefore, this fern could be possibly used as a natural green fertilizer and possibly eliminate usage of nitrogen fertilizers propagating more sustainable agricultures practises. Authors say that having both the genomes of cyanobacteria and now the fern, research can be focused on developing and adopting such sustainable practises. Interestingly, fern Azolla has already been added in rice paddies as green manure by Asian farmers for more than 1000 years.

ນັກຄົ້ນຄວ້າຍັງໄດ້ກໍານົດ gene ທີ່ສໍາຄັນທີ່ດັດແປງຕາມທໍາມະຊາດ (ຢາຂ້າແມງໄມ້) ໃນຜັກກູດທີ່ເຫັນວ່າມີຄວາມສາມາດໃນການຕ້ານແມງໄມ້. ເຊື້ອນີ້ເມື່ອຖືກໂອນໄປຫາຕົ້ນຝ້າຍໃຫ້ການປົກປ້ອງຢ່າງໃຫຍ່ຫຼວງຈາກແມງໄມ້. gene 'ຢາຂ້າແມງໄມ້' ນີ້ຄິດວ່າຈະຖືກໂອນຫຼື 'ຂອງຂວັນ' ຈາກເຊື້ອແບັກທີເຣັຍໃສ່ຜັກກູດແລະເຫັນວ່າເປັນອົງປະກອບສະເພາະຂອງເຊື້ອສາຍຂອງຜັກກູດເຊັ່ນວ່າມັນຖືກຖ່າຍທອດຢ່າງສໍາເລັດຜົນຈາກລຸ້ນສູ່ລຸ້ນ. ການຄົ້ນພົບການປົກປັກຮັກສາທີ່ມີທ່າແຮງຈາກແມງໄມ້ແມ່ນມີຄວາມຜູກມັດທີ່ຈະມີຜົນກະທົບທີ່ເຂັ້ມແຂງຕໍ່ການປະຕິບັດດ້ານກະສິກໍາ.

This study shows that ‘pure science’ of unravelling first ever genomic information from ferns is a major step in the direction of uncovering and understanding crucial plant genes. It also helps in a better understanding of the evolutionary history of ferns i.e. how their features have evolved over the generations. Understanding of plants is very crucial to explore and comprehend how flora and fauna exist together amicably on our ດາວ and such research should be given importance rather than labelling it as something which is not significant enough. After sequencing Azolla filiculoides and Salvinia cucullata, more than 10 fern species are already in pipeline for further research.

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{ທ່ານສາມາດອ່ານເອກະສານການຄົ້ນຄວ້າຕົ້ນສະບັບໄດ້ໂດຍການຄລິກທີ່ລິ້ງ DOI ທີ່ໃຫ້ໄວ້ຂ້າງລຸ່ມນີ້ໃນລາຍຊື່ແຫຼ່ງທີ່ອ້າງອີງ}

ແຫຼ່ງຂໍ້ມູນ (s)

1. Fay-Wei L et al. 2018. Fern genomes elucidate land plant evolution and cyanobacterial symbioses. ພືດ ທຳ ມະຊາດ. 4(7). https://doi.org/10.1038/s41477-018-0188-8

2. Fernbase https://www.fernbase.org/. [ເຂົ້າ​ເຖິງ 18 ກໍລະກົດ 2018].

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